Shi noted that mast cell hypertrophy in diabetic patients lcms and obese fat tissue has occurred, s

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The two Harvard biochemist - Guo-Ping Shi and Liu Jian - mast cells examined lcms as part of the immune system that are involved in the healing of damaged tissue. In some cases, the mast cells are produced in excess lcms quantity, disintegrate and debris into the surrounding lcms tissue. This process results in inflammation lcms and may be associated with asthma and other allergies.
Shi noted that mast cell hypertrophy in diabetic patients lcms and obese fat tissue has occurred, so the thought occurred to him: whether the regulation lcms of mast cells could influence diabetes?
The two researchers lcms often available without a prescription for allergy tried experiments in mice, an active substance ketotifen and cromolyn medicine. Obese and diabetic rodents were divided into four groups; lcms one group caught a healthy diet; the other lived in the usual diet, and next to it was one of the two times; the third was also one of the two active ingredients and yet also diétáztatták; the last group was used as control.
The first group is somewhat reduced the symptoms in the second hand, a dramatic improvement was observed in both the weight of researchers, both in respect of diabetes, the animals of the third group is almost 100 percent recovered.
The next step of the study, the researchers lcms genetically modified mice, mast cells were not able to produce. lcms These mice remained and did not have diabetes, even though it sugary and fatty diets have been kept for three months are slim.
The Nature Medicine study found three other close relationship between obesity, diabetes and immune system lcms malfunction. In the immune system, the role of T cells studied in the development lcms of insulin resistance in obese mice. The condition is thought to be effective for both drugs and even vaccine may lead to new results.